CELLULAR AND MICROBIOLOGICAL IN VITRO ASSAYS, CHEMICAL ANALYSIS, CONSULTING AND SCIENTIFIC SERVICES TO COMPANIES
 
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  HEALTH CARE CONSUM PRODUCTS
in vitro and in vivo efficacy and safety studies

IN VITRO ASSAYS

•  Cytotoxicity tests

•  Eye irritation testing

•  Skin irritation testing

•  Sensistisation testing

•  Phototoxicity assays

•  SPF assay

•  Antioxidant/scavenging activity on skin-derived cells

•  Anti-inflammatory activity on skin-derived cells

•  Cell proliferation assays on skin-derived cells

•  Percutaneous absorption test on 3D human reconstituted epidermis

•  Barreer effect assay on on 3D human reconstituted epidermis

•  Keratolytic effect assay on 3D human reconstituted epidermis

•  Healing and vasoprotective activity on human endothelial cells

•  Antiage and dermal substantive effect on derma-derived cells

•  Sebum regulating activity

•  Specific assays of beiochemical functionality on skin-derived cells
   (inhibition/stimulation of enzymes, ECM proteins, Cytokines release)

•  5-alpha reductase inhibition

•  Melanogenesis modulation
   (increase of stimulation or inhibitions of the cell pigmentation)

•  Immune system stimulation/inhibition

•  Ames test and mutagensis assays

•  Ecotoxicity assays

CHEMICAL ANALYSIS

•  Instrumental analysis in HPLC, GC, GC-MS, IR, UV-VIS, AAS, ICP.

•  Actives quali/quantitative determination

•  Preservatives titration

•  Color and pigments determination

•  Analysis and stability of sun filters

•  Contaminants analysis (pesticides, nitrosamines, heavy metlas,…)

•  Metals content determination

•  Release assays for Nickel and othert sensitising metals

•  Melting and drop point determination

•  ICH stability testing

MICROBIOLOGICAL ANALYSIS

• Total microbic count

•  Research of specific microorganisms

•  In use test to predict the PAO value

•  Microbiological stability assays

•  Challenge test and RDV determination

ANIMAL TESTING

• Acute toxicity

•  Eye irritation

•  Skin irritation

•  Sensitisation

 CLINICAL TESTING
    (in convention with external human investigation centres and laboratories)

• Patch test

•  In use test

•  Anti-wrinkles test

•  Anticellulitis test

•  Skin mositurisation testing

•  Firmino activity testing

•  Antiacne and sebonormalizing activity testing

•  Antiplaque activity

•  Sniff test

•  Many others on request

NEWS

15/12/2011
CHALLENGE TEST
- On the bases of the new ISO standard draft method n. 11930 for the assessment of the efficacy of the preservative system in comsmetics, a validation of the microbiological analytical method on each single matrix will be required, as it already happens with the Pharmacopoeia method. The standard will be published the next year and will support in the best way the safety evaluation need in compliance with the new Regulation 1223/2009, annex I. Start to plan today the updating of your product inf [to be continued]

15/12/2011
UNIVERSITARY MASTER IN SCIENCE OF COSMETIC AND DERMATOLOGICAL PRODUCTS
will start at the University of Camerino (Italy) in January 2012. Theoretical and practical sessions will be held from January to July 2012. See the enclosed brochure. For information contact the professor Piera di Martino pho +39 320 7985643; e-mail: piera.dimartino@unicam.it [to be continued]

15/12/2011
IN VIVO EFFICACY TEST FOR COSMETICS
the new test based on the laser blu technique (DERMA-TOP) is now available for the quantitative determination and visual identification of wrinkles, skin profilometry and tridimensional details of the face and body surface. High quality 3D imaging, very quick data acquisition, ability to identify and monitor skin surface and volume details in the very same site at different acquisition end-times. It is the ideal technique to point out and scientifically support the reduction of the under-eye ba [to be continued]

All News

Sede legale, direzione, uffici e laboratorio analisi: Via 42 Martiri, 213/B – 28924 Verbania (VB)
Tel +39 0323 586239/496041 – Fax +39 0323 496877 - info@abich.it
Centro studi clinici e cosmetologici: Via Bruno Buozzi, 4 – 20090 Vimodrone (MI)