Skin elasticity and toning

Evaluation of skin compactness and elasticity

Regulatory reference: Guidelines to Commission Regulation (EU) No 655/2013
Claim: Firming efficacy, Improves skin tone and smoothness and Improves skin elasticity
Application field: Visage and body products.
Description of the test: Measurement of R0 and R2 parameters on 20 healthy volunteers. Instrument: MPA580 Cutometer® for the scientific quantification of the viscoelasticity of the skin.
Manufacturer: Courage-Khazaka GmbH (Germany).
Posted in Firming efficacy, Improves skin elasticity, Improves skin tone and smoothness, Skin elasticity and toning, Claim for cosmetics

Evaluation of the activation of the synthesis of collagen and fibronectin

Regulatory reference: Proprietary method
Claim: Activates the synthesis of collagen, elastin, fibronectin
Application field: Finished products and active ingredients.
Description of the test: Real time PCR analysis of the expression of collagen and fibronectin, compared to an untreated control, to determine the efficacy of a product or ingredient in activating the synthesis of these proteins involved in maintaining skin elasticity and prevent aging.
Posted in Anti age, Skin elasticity and toning, Claim for cosmetics, Activates the synthesis of collagen, elastin, fibronectin

Evaluation of the activation of the synthesis of collagen and elastin

Regulatory reference: Proprietary method
Claim: Activates the synthesis of collagen, elastin, fibronectin
Application field: Finished products and active ingredients.
Description of the test: Quantitative analysis of the effect of the tested product in increasing the synthesis of collagen and elastin. The test is performed on several concentration and time points using real time PCR on cultured cell lines. The test can be performed on human keratinocytes or fibroblasts.
Posted in Anti age, Skin elasticity and toning, Claim for cosmetics, Activates the synthesis of collagen, elastin, fibronectin

Quantification of the increase in proliferation and activation of protein synthesis on skin cells

Regulatory reference: Proprietary method
Claim: Anti-aging and Redensifies and tones the epidermis
Application field: Finished products and active ingredients.
Description of the test: Quantitative evaluation of the efficacy of a product or active ingredient in increasing cell proliferation and protein synthesis. MTT test and protein quantification at different time intervals. The test can be performed on human keratinocytes or fibroblasts.
Posted in Anti age, Anti-aging, Redensifies and tones the epidermis, Skin elasticity and toning, Claim for cosmetics
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