|Regulatory reference:||OECD 129: on using cytotoxicity tests to estimate starting doses for acute oral systemic toxicity tests; |
EURL-ECVAM 2011: follow-up study on the predictive capacity of the 3T3 Neutral Red Uptake cytotoxicity assay to correctly identify substances not classified for acute oral toxicity under the EU CLP system.
|Claim:||Biocompatible and Non citotoxic|
|Application field:||Chemical substances or mixtures.|
|Description of the test:||The in vitro LD50 prediction test is designed to test chemicals or mixtures by evaluating their cytotoxic effect on an in vitro model of BALB/c 3T3 murine fibroblasts.|